Noradrenergic circuits in the forebrain control affective responses to novelty
نویسندگان
چکیده
منابع مشابه
Forebrain and brain stem neural circuits contribute to altered sympathetic responses to heating in senescent rats.
Acute heating in young rats increases visceral sympathetic nerve discharge (SND); however, renal and splanchnic SND responses to hyperthermia are attenuated in senescent compared with young Fischer 344 (F344) rats (Kenney MJ and Fels RJ. Am J Physiol Regul Integr Comp Physiol 283: R513-R520, 2002). Central mechanisms by which aging alters visceral SND responses to heating are unknown. We tested...
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Professor Richard F. Thompson and his highly influential work on the brain substrates of associative learning and memory have critically shaped my research interests and scientific approach. I am tremendously grateful and thank Professor Thompson for the support and influence on my research and career. The focus of my research program is on associative learning and its role in the control of fu...
متن کاملNoradrenergic enhancement of amygdala responses to fear.
Multiple lines of evidence implicate the basolateral amygdala (BLA) and the noradrenergic (norepinephrine, NE) system in responding to stressful stimuli such as fear signals, suggesting hyperfunction of both in the development of stress-related pathologies including anxiety disorders. However, no causative link between elevated NE neurotransmission and BLA hyperresponsiveness to fear signals ha...
متن کاملNovelty as a dimension in the affective brain
Many neuroscience studies have demonstrated that the human amygdala is a central element in the neural workspace that computes affective value. Emerging evidence suggests that novelty is an affective dimension that engages the amygdala independently of other affective properties. This current study is the first in which novelty, valence, and arousal were systematically examined for their relati...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 2020
ISSN: 0033-3158,1432-2072
DOI: 10.1007/s00213-020-05615-8